This study assessed the sources of poultry drug information and level of compliance among farmers in Abuja FCT, Nigeria. Multistage sampling technique was used select 165 poultry farmers from Gwagwalada and Bwari area councils for this study. The findings revealed that majority of farmers (60%) were between 30-50 years old, 70% had secondary education or higher, and 80% were male. Majority 82.4% have primary education, with a mean of 8 years of formal education. The result also revealed that Enrofloxacin, Oxytetracycline, Doxycycline, Furazolidone, NeocerylR, and Gentamycin were the major drugs utilized by poultry farmers. However, administering drugs using the recommended route and technique (????̅=2.50), Maintain accurate records of drug administration (????̅=2.50), store drugs in a cool dry place and protect them from sunlight (????̅=2.40) and avoid using drugs for non-approved indications or as growth promoters (????̅=2.40) had high level of compliances of poultry drug information among the farmers in the study area. Furthermore, age, level of education, farming experience, compatibility, relative advantage, complexity, training received and farmers’ perception were the factors influencing the level of compliance to poultry drug information and level of farmer’s access to information’ in the study area. Poultry farmers in Abuja FCT demonstrate moderate to high compliance with drug usage guidelines, influenced by education, experience, and access to information. Therefore, it is recommended that targeted training programme and improved access to veterinary information should be promoted by the extension organization to enhance compliance and responsible drug use among poultry farmers.